NFL Week 4 Picks Against the Spread, Tips and Predictions
Published 12:31 am Wednesday, September 25, 2024
After analyzing the 16 games on the Week 4 slate in the NFL, our best against-the-spread selection is Raiders -1. For more tips, which could lead to parlay opportunities, scroll down.
Find an edge on the competition and take advantage of our spread picks for the NFL. BetMGM has all the information you need to start wagering on the NFL.
NFL Picks Against the Spread – Week 4
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CLE-LV | NO-ATL | TEN-MIA | PIT-IND | PHI-TB | MIN-GB | BUF-BAL | LAR-CHI | WAS-ARI | SEA-DET | CIN-CAR | DAL-NYG | JAX-HOU | DEN-NYJ | KC-LAC | NE-SF
Pick: Raiders -1 vs. Browns
- Matchup: Cleveland Browns at Las Vegas Raiders
- Projected Winner & Margin: Raiders by 6.3 points (Bet on this game at BetMGM)
- Spread: Raiders -1
- Time: 4:25 PM ET
- Date: Sept. 29
- TV Channel: CBS
- Live Stream: Paramount+ | Fubo (Regional restrictions may apply)
Pick: Saints +1.5 vs. Falcons
- Matchup: New Orleans Saints at Atlanta Falcons
- Projected Winner & Margin: Saints by 0.4 points (Bet on this game at BetMGM)
- Spread: Falcons -1.5
- Time: 1:00 PM ET
- Date: Sept. 29
- TV Channel: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
Pick: Dolphins +1.5 vs. Titans
- Matchup: Tennessee Titans at Miami Dolphins
- Projected Winner & Margin: Dolphins by 5.0 points (Bet on this game at BetMGM)
- Spread: Titans -1.5
- Time: 7:30 PM ET
- Date: Sept. 30
- TV Channel: ESPN
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
Pick: Steelers -2 vs. Colts
- Matchup: Pittsburgh Steelers at Indianapolis Colts
- Projected Winner & Margin: Steelers by 4.5 points (Bet on this game at BetMGM)
- Spread: Steelers -2
- Time: 1:00 PM ET
- Date: Sept. 29
- TV Channel: CBS
- Live Stream: Paramount+ | Fubo (Regional restrictions may apply)
Pick: Buccaneers +2.5 vs. Eagles
- Matchup: Philadelphia Eagles at Tampa Bay Buccaneers
- Projected Winner & Margin: Buccaneers by 2.5 points (Bet on this game at BetMGM)
- Spread: Eagles -2.5
- Time: 1:00 PM ET
- Date: Sept. 29
- TV Channel: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
Pick: Vikings +2.5 vs. Packers
- Matchup: Minnesota Vikings at Green Bay Packers
- Projected Winner & Margin: Packers by 1.2 points (Bet on this game at BetMGM)
- Spread: Packers -2.5
- Time: 1:00 PM ET
- Date: Sept. 29
- TV Channel: CBS
- Live Stream: Paramount+ | Fubo (Regional restrictions may apply)
Pick: Bills +2.5 vs. Ravens
- Matchup: Buffalo Bills at Baltimore Ravens
- Projected Winner & Margin: Ravens by 1.0 points (Bet on this game at BetMGM)
- Spread: Ravens -2.5
- Time: 8:20 PM ET
- Date: Sept. 29
- TV Channel: NBC
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
Pick: Rams +3 vs. Bears
- Matchup: Los Angeles Rams at Chicago Bears
- Projected Winner & Margin: Rams by 1.1 points (Bet on this game at BetMGM)
- Spread: Bears -3
- Time: 1:00 PM ET
- Date: Sept. 29
- TV Channel: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
Pick: Cardinals -3.5 vs. Commanders
- Matchup: Washington Commanders at Arizona Cardinals
- Projected Winner & Margin: Cardinals by 7.3 points (Bet on this game at BetMGM)
- Spread: Cardinals -3.5
- Time: 4:05 PM ET
- Date: Sept. 29
- TV Channel: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
Pick: Seahawks +3.5 vs. Lions
- Matchup: Seattle Seahawks at Detroit Lions
- Projected Winner & Margin: Lions by 2.9 points (Bet on this game at BetMGM)
- Spread: Lions -3.5
- Time: 8:15 PM ET
- Date: Sept. 30
- TV Channel: ABC
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
Pick: Panthers +4.5 vs. Bengals
- Matchup: Cincinnati Bengals at Carolina Panthers
- Projected Winner & Margin: Panthers by 0.9 points (Bet on this game at BetMGM)
- Spread: Bengals -4.5
- Time: 1:00 PM ET
- Date: Sept. 29
- TV Channel: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
Pick: Giants +5.5 vs. Cowboys
- Matchup: Dallas Cowboys at New York Giants
- Projected Winner & Margin: Cowboys by 1.1 points (Bet on this game at BetMGM)
- Spread: Cowboys -5.5
- Time: 8:15 PM ET
- Date: Sept. 26
- TV Channel: Amazon Prime Video
- Live Stream: Watch this game on Prime Video (Regional restrictions may apply)
Pick: Texans -7 vs. Jaguars
- Matchup: Jacksonville Jaguars at Houston Texans
- Projected Winner & Margin: Texans by 8.5 points (Bet on this game at BetMGM)
- Spread: Texans -7
- Time: 1:00 PM ET
- Date: Sept. 29
- TV Channel: CBS
- Live Stream: Paramount+ | Fubo (Regional restrictions may apply)
Pick: Broncos +7.5 vs. Jets
- Matchup: Denver Broncos at New York Jets
- Projected Winner & Margin: Broncos by 1.3 points (Bet on this game at BetMGM)
- Spread: Jets -7.5
- Time: 1:00 PM ET
- Date: Sept. 29
- TV Channel: CBS
- Live Stream: Paramount+ | Fubo (Regional restrictions may apply)
Pick: Chargers +8 vs. Chiefs
- Matchup: Kansas City Chiefs at Los Angeles Chargers
- Projected Winner & Margin: Chargers by 2.4 points (Bet on this game at BetMGM)
- Spread: Chiefs -8
- Time: 4:25 PM ET
- Date: Sept. 29
- TV Channel: CBS
- Live Stream: Paramount+ | Fubo (Regional restrictions may apply)
Pick: 49ers -10 vs. Patriots
- Matchup: New England Patriots at San Francisco 49ers
- Projected Winner & Margin: 49ers by 10.6 points (Bet on this game at BetMGM)
- Spread: 49ers -10
- Time: 4:05 PM ET
- Date: Sept. 29
- TV Channel: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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